Associate Scientist, Formulation Development (DPDT)

Regeneron's Drug Product Development and Technology Group is seeking an Associate Scientist to support all stages of pre-clinical, clinical, commercial formulation, and drug product development for various drug product modalities. In this role, you may develop, qualify, and apply biochemical and biophysical methods to carry out developability assessment and formulation development studies on monoclonal antibody-based therapeutics, to support drug substance and drug product development.

A Typical Day in the Role of Associate Scientist May Include the Following:

• Design and execute phase-appropriate formulation development studies, such as formulation screening, stability, and compatibility studies, to support formulation and drug product development for early and late-stage development programs.

• Conduct biochemical and biophysical assessments and pre-formulation studies to support evaluation of preclinical drug candidates.

• Characterize drug product (lyophilized or liquid) formulation to support process development and manufacturing of clinical drug substances and drug products.

• Provide technical support for development, technology transfer and manufacture of drug substance and drug products and collaborate with cross-functional teams.

• Develop and qualify analytical methods for critical quality attributes to support formulation development, drug product process development, and stability testing for programs in all development stages. 

• Document findings and lab records in electronic laboratory notebook by following the organizational best practices and policies.

• Author protocols, technical documents for internal use and support regulatory filings.

• Participate in meetings and present study results in department meetings or cross-functional team meetings.

• Take part in the general laboratory and instrument maintenance.

This Role Might Be for You If:

• You are highly organized, detail-oriented, self-motivated, and passionate about science and innovation.

• You excel when working in a fast-paced environment and can manage multiple tasks effectively.

• You are a strong team player.

• You have excellent interpersonal, oral, and written communication skills.

This role requires a B.S or MS degree in Pharmaceutical Sciences, Chemistry, Biochemistry, Biophysics, Biomedical Engineering, Analytical Chemistry, Chemical Engineering, or a related discipline with 0-3 years of hands-on laboratory experience. Relevant industry or intern experience is preferred. The ability to design and execute experiments, as well as interpret, document, and communicate results with minimal supervision is required. Strong technical knowledge base and relevant experience with protein/peptide chemistry, biophysical/biochemical characterization of proteins, bioanalytical method development and biomolecule product development is desirable. Hands-on experience with biochemical and biophysical techniques for protein characterization, including chromatography (SEC, IEX, RP), viscosity, gel electrophoresis (CE-SDS, MCE, cIEF, iCE), particle size (DLS, HIAC, MFI), spectroscopy (UV-Vis, CD, AUC, fluorescence), and thermostability characterization (DSC, DSF) is desirable.

 

Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We are committed to building a workplace with an inclusive culture. Regeneron is an equal opportunity employer and all  qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law. Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.

 

Where necessary, we disclose salary ranges for roles in all countries in which we operate.  The final offer will be determined within the relevant range based on the country of employment, specific role level, and your skills and experience. In some countries, collective bargaining agreements (CBAs) may apply and influence certain elements of pay or benefits.  Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family support benefits. For additional information about Regeneron benefits in the U.S., please visit https://careers.regeneron.com/en/working-at-regeneron/total-rewards/. For other locations, additional information will be provided during the recruitment process.  If you have any questions, please speak with your recruiter. 

Please be advised that at Regeneron, we believe we do our best work when we are together. For that reason, many roles are required to be performed on‑site. Please speak with your recruiter and hiring manager for more information about on‑site expectations for your role and location.

As part of the recruitment process, certain background checks may be conducted in accordance with the laws of the country where the position is based. The purpose of such checks is to verify certain information prior to the commencement of employment such as identity, right to work and educational qualifications.

For jobs in Canada: this posting is for an existing position.

Salary Range (annually)

$70,300.00 - $110,100.00