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South San Francisco, California, United States
Onsite
Septerna is a biotechnology company based in South San Francisco, CA on a mission to develop life-changing medicines for patients with the vision to become the industry-leading G protein-coupled receptor (GPCR)-focused drug discovery company. The company’s Native Complex Platform™ recapitulates GPCRs with their native structure, function, and dynamics outside of the cellular context. This approach enables novel access to modern structural and screening technologies used in industrial-scale drug discovery for the entire class of GPCRs. Septerna has an emerging pipeline of GPCR-targeted small molecule programs, many in the Endocrinology space, with potential for growth to target many GPCRs that have been undruggable and unexploited to date.
We are excited to expand our multidisciplinary team of individuals focused on creating revolutionary medicines to address the unmet needs of patients. At Septerna we strive to embrace diversity of thought, expertise, and background through collaboration. To join our ambitious team, be prepared to bring your real self to work every day; grow and learn from a talented team of drug hunters, scientists, and business professionals; and contribute your passion, creativity, and energy to accomplish our mission. We share a fearless pursuit of ground-breaking innovations and cultivate an environment where our employees succeed by learning from each other and working as a team.
We are committed to the development of meaningful therapeutics for patients with indications of high unmet need. This is a tremendous opportunity to work with talented individuals on the frontlines of therapeutic discovery and development. You will directly help move therapies through preclinical research, positioning them for success in the clinic. The successful candidate will add their passion, unique talents, and expertise to a dynamic team motivated to discover new disease-modifying therapeutics for patients in a fast-paced environment.
For more information see: www.septerna.com.
THE ROLE
The Associate Scientist will primarily be responsible for the development and conduct of in vivo, ex vivo, as well as in vitro studies in Translational Sciences to support the advancement of Septerna’s small molecule drug discovery pipeline. They will work independently and collaboratively in an inter-disciplinary setting to design and execute experiments in preclinical models to understand in vivo pharmacology, establish PK/PD relationships, and inform the efficacy of Septerna’s therapeutic candidates. They will help generate and analyze functional in vitro, in vivo, and ex vivo data to determine the therapeutic mechanism of action, and rank candidates for preclinical development. They may also engage in biomarker discovery efforts by utilizing a variety of in vitro, in vivo and ex vivo models to enable and inform effective therapeutic development. This role is expected to be primarily in the lab with some desk work.
We are committed to the development of meaningful therapeutics for patients with indications of high unmet need. This is a tremendous opportunity to work with talented individuals on the frontlines of therapeutic discovery and development. You will help move therapies through preclinical development, positioning them for success in the clinic. The successful candidate will add their passion, unique talents, and expertise to a dynamic team on the frontlines of innovative therapeutic development.
The position is based in South San Francisco, CA.
*Title commensurate with experience
Key Responsibilities include but are not limited to:
REQUIRED EDUCATION, SKILLS & EXPERIENCE
The anticipated salary range for candidates who will work in South San Francisco, CA is $100,000 - $110,000. Individual pay may vary based on additional factors, including, and without limitation, job-related skills, experience, work location and relevant education or training. Septerna's compensation package also includes benefits, stock options, and annual target bonus for full-time positions.