Associate Staff Scientist (CUSToM) Immunoengineering/ Organoid generation

Are you enthusiastic about working on Organoids at the interface of academic research and industry applications? Do you want to be part of a great interdisciplinary, international team?

The Accelerator Lab at the Center for Stem Cells and Organoid Medicine (CuSTOM) at Cincinnati Children’s Hospital is seeking an Associate Staff Scientist with a focus on immunocompetent Organoid models.

This is a rare opportunity to join CuSTOM at Cincinnati Children’s, where we revolutionize drug discovery and development, personalized medicine, and improve patient care using advances in developmental biology and stem cell technologies. We offer a highly rewarding scientific environment with ample learning opportunities and an expectation to publish new findings. There's no better place to make a difference in medicine, patients, and society.

Established in 2019, CuSTOM Accelerator is a state-of-the-art laboratory focused on addressing major challenges posed to bench-to-bedside translation of stem cell research. At CuSTOM Accelerator, we work at the intersection of academia and industry to develop organoid-based platforms that provide an unprecedented opportunity to bridge preclinical and clinical trials, revolutionizing personalized medicine and improving patient care.

Your tasks:

· Establishing and applying organoid-based HTS/HSC platforms

· Isolation, culture, and characterization of immune cells

· Planning, conducting, and analyzing assays using organoid models

· Evaluation of immune phenotypes in the platform

· Presentation and publication of research results

Candidate profile:

· Completed PhD in natural sciences or engineering

· Previous postdoctoral experience in academic or industry research is an advantage

· Comprehensive practical experience in (primary, stem cell) cell culture, organoids, or organs-on-chips, and microscopy

· In-depth knowledge with a focus on immunoengineering

· Experience with stem cells and organoids is desirable

· Willingness to engage in interdisciplinary research activities (life science and engineering)

· Very good knowledge of English as well as a structured, independent way of working

What we offer:

· The opportunity to work within an exciting multidisciplinary project and delve into highly innovative research topics

· A highly motivated, competent, and multidisciplinary team with scientific and technical staff members

· Excellent technical equipment and laboratory infrastructure

· An exciting, varied, and innovative working environment and excellent technical equipment

JOB RESPONSIBILITIES

• Conduct Research - Design, execute and record laboratory experiments; apply standard scientific/research protocols to experiments, research and improve current methods and evaluate innovative techniques. Design and perform experiments and record data according to research protocol. Independently reproduce, evaluate, research and improve techniques currently used. Adapt new methods to existing procedures and modify current experiments through scientific knowledge and intuition. Maintain accurate and detailed records of all laboratory work and experiments. Develop, set-up and verify new procedures in the laboratory. Standardize and establish new published procedures; evaluate innovative techniques. Develop new assays and new protocols; design formats. Discuss relevant insights about experimental results with Director and provide useful recommendations and analysis. Troubleshoot and correct erroneous results or problems with laboratory equipment. Maintain and repair equipment; monitor proper use by personnel. Maintain optimal protocol and assay accuracy by conducting regular quality and reproducibility checks. Demonstrate performance at work, consistency in carrying out instructions, accuracy & attention to detail, achieving expected results & continuous improvement.

• Publish - Draft, write and edit scientific reports, papers, journal articles and abstracts. Present at local, national and international scientific meetings.

• Teamwork - Train and supervise the work of other laboratory personnel as appropriate. Maintain an integral role in the laboratory's meetings, presentations and publications. Present information on research and laboratory work to others at laboratory meetings, journal clubs and seminars. Demonstrate attendance and punctuality, ability to work independently & display initiative and dedication

• Financial Management - Assist in preparing, writing and maintaining fiscal budget. Monitor expenditures and prepare capital expenditure requests. Prepare, approve and initiate check requests; track funding, maintain accurate balance and resolve any discrepancies.

• Leadership - May act as a mentor to more junior staff, serve as the contact for resolution of complex issues, provide education, guidance and work direction. May provide input and feedback to managers on hiring decisions, professional development and performance management.

JOB QUALIFICATIONS

• PhD

• 3+ years of work experience in a related job discipline

 

Primary Location

Location R

 

Schedule

Full time

 

Shift

Day (United States of America)

 

Department

CuSTOM Program

 

Employee Status

Regular

 

FTE

1

 

Weekly Hours

40

At Cincinnati Children’s, we come to work with one goal: to make children’s health better. We believe in a holistic team approach, both in caring for patients and their families, and in advancing science and discovery. We strive to do better and find energy and inspiration in our shared purpose. If you want to be the best you can be, you can do it at Cincinnati Children’s. 

 Cincinnati Children's is: 

• Recognized by U.S. News & World Report as a top 10  best Children's Hospitals in the nation for more than 15 years 

• Consistently among the top 3 Children's Hospitals for National Institutes of Health (NIH) Funding 

• Recognized as one of America’s Best Large Employers  (2025), America’s Best Employers for New Grads (2025) 

• One of the nation's America’s Most Innovative Companies as noted by Fortune 

• Consistently certified as great place to work 

• A Leading Disability Employer as noted by the National Organization on Disability 

• Magnet® designated for the fourth consecutive time by the American Nurses Credentialing Center (ANCC) 

 We Embrace Innovation—Together.  We believe in empowering our teams with the tools that help us work smarter and care better. That’s why we support the responsible use of artificial intelligence. By encouraging innovation, we’re creating space for new ideas, better outcomes, and a stronger future—for all of us.

Comprehensive job description provided upon request.

Cincinnati Children’s is proud to be an Equal Opportunity Employer committed to creating an environment of dignity and respect for all our employees, patients, and families. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, age, genetic information, national origin, sexual orientation, gender identity, disability or protected veteran status. EEO/Veteran/Disability