Director, Commercial Insights & Analytics - PNH

Are you ready to turn complex data into crucial actions that shape US Commercial strategy and accelerate impact for patients?

As Director, Commercial Insights & Analytics, you will be the connective force between data, strategy, and execution—partnering closely with US hematology and nephrology leaders to surface opportunities and respond to risks with clarity and speed.

Based in Boston, MA, you will be a visible leader who integrates market research, forecasting, and analytics into recommendations that drive growth. You will translate signals from the market into plans that influence portfolio decisions and brand performance, building tools and models that scale insight across teams. How will you use your ability to see around corners to inform choices that matter now and in the long term?

Accountabilities:

• Opportunity sensing and decision support: Proactively find opportunities and threats by combining data with business context to inform timely, high-impact decisions across the US Commercial organization.
• Cross-functional strategic advising: Serve as a central point of expertise, partnering with Marketing Leadership, business units, and Business Operations to frame and answer key strategic questions.
• Forecasting leadership: Build US long-term patient-based and US short-term TRx/NBRx forecasting models that synthesize robust inputs, benchmark against analogs, and align with US and key market assumptions.
• Executive storytelling: Expertly present forecasts, methodologies, and assumptions through multiple channels—translating complexity into clear, decision-ready narratives for senior commercial and clinical partners.
• Data rigor and modeling perfection: Ensure objectivity by selecting the right data sources, applying industry-leading modeling approaches, and conducting sensitivity analyses on critical variables.
• Commercial strategy enablement: Collaborate with leadership and Business Operations to convert insights into strategies and tactics that directly advance growth and optimize performance.
• Tooling and methods innovation: Evolve analytical tools, processes, and quantitative methods to increase speed, accuracy, and adoption across teams.
• Performance insight and planning: Lead monthly and quarterly business reviews that diagnose past performance and illuminate leading indicators of future growth.
• Agile analysis: Deliver high-quality, adaptable solutions to ad-hoc analytic requests, accelerating decision cycles and removing ambiguity for collaborators.

Essential Skills/Experience:

• Outstanding communication and creative problem-solving skills
• Understanding of organizational dynamics and ability to influence at all levels of the organization
• Confidence and ability to present complex information concisely and effectively to all audiences, including senior leaders and groups
• Strong analytical and organization skills, capable of handling multiple projects simultaneously
• Ability to anticipate future Commercial trends and to integrate that context into business practices
• Desire and ability to learn/implement new tools and capabilities
• Experience leading technical teams and individuals across geographies
• Diligent, self-starter, able to work both independently and in a team environment
• Bachelor’s Degree in Computer Science, Engineering, Business, Finance, or other quantitative field
• The duties of this role are generally conducted in an office environment. As is typical of an office-based role, employees must be able, with or without an accommodation to: use a computer; engage in communications via phone, video, and electronic messaging; engage in problem solving and non-linear thought, analysis, and dialogue; collaborate with others; maintain general availability during standard business hours.

Desirable Skills/Experience:

• 7+ years of experience in Business Analytics and/or Financial Analysis
• MBA or advanced quantitative rigor degree preferred
• Prior experience in rare disease

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions.

That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

Why AstraZeneca:

Here you will use analytics to make a measurable difference for people with rare and devastating conditions, working shoulder-to-shoulder with colleagues in marketing, medical, and R&D who rally around real patient stories and real business decisions. We bring unexpected teams together—data scientists, brand leaders, and clinicians at the same whiteboard—to challenge assumptions and move faster with integrity. You will shape strategy in a setting that blends the agility of a biotech with the reach of a global company, supported by leaders who value kindness alongside ambition and who invest in your growth as you take on complex problems that truly matter.

Call to Action:

Step into a high-impact seat where your insights will guide pivotal choices—send us your resume and lead the data-driven decisions that move medicine forward.

The annual base pay for this position ranges from US $194,571 & $291,856 Our positions offer eligibility for various incentives—an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans. 

Date Posted

07-Jul-2026

Closing Date

06-Jul-2026

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.