**Exonic Biosciences · Dogpatch, San Francisco**
**$120K–$180K a year + equity**
Exonic is building AI systems for programmable biology.
We train multimodal foundation models on large-scale biological datasets to design synthetic non-coding DNA. We experimentally validate our AI-designed systems in mammalian cells, with current applications in cell-type targeting and viral vector biomanufacturing.
Our core focus is synthetic regulatory DNA. We have already generated strong in vitro cell-type targeting results and are expanding our internal experimental platform in San Francisco.
We are looking for an ambitious experimental scientist to take ownership of Exonic’s wet-lab work and help push the platform into new directions.
You would work directly with the founder as one of the first people in the company.
**What you’ll work on**
* Own and execute experimental validation of AI-designed regulatory DNA
* Design and run cell-based assays for synthetic enhancer and expression systems
* Help advance programs in cell-type targeting and AAV manufacturing
* Help shape Exonic’s experimental roadmap as the company grows
**Relevant experience**
* Molecular biology, synthetic biology, regulatory genomics, or gene therapy
* Mammalian cell culture and cell-based assays
* Cloning, plasmid design, transfection, qPCR/ddPCR, sequencing, flow, luciferase, or related workflows
* AAV biology/manufacturing experience is a major plus
We care most about ownership, execution speed, and comfort with ambiguity.
This is an early-stage role with autonomy, and the opportunity to build the biological engine of an AI-native synthetic DNA company.
**Location:** San Francisco / MBC BioLabs
Visa sponsorship is not available for this role.
