ROLE SUMMARY
Reporting to the Chief Oncology Medical Officer, the Head of Oncology Medical Affairs Business Operations leads the day-to-day business operations, planning, governance, resource management, communications, and organizational enablement required to advance the priorities of the Oncology Medical Affairs organization. As a member of the Oncology Medical Affairs Leadership Team (OMALT), this leader serves as a trusted operational partner to the Chief Oncology Medical Officer and works across Medical Affairs, Oncology, Research, Development, Commercial, People Experience, Finance, Communications, and other enabling functions to translate priorities into coordinated execution. The role combines strong business acumen, disciplined operational leadership, and an understanding of the scientific and healthcare environment to strengthen leadership team effectiveness, remove barriers, manage dependencies, and enable measurable impact for patients and the oncology community.
ROLE RESPONSIBILITIES
- Business operations and leadership enablement. Lead day-to-day business operations for the Chief Oncology Medical Officer, including prioritization and coordination of key interactions, meetings, presentations, deliverables, and organizational commitments. Anticipate operational needs, surface risks and dependencies, and ensure timely follow-through on decisions and actions.
- Business planning and execution. Lead annual, semester, and longer-range business planning for Oncology Medical Affairs, including development, alignment, implementation, and tracking of organizational goals, success measures, and execution plans. Provide clear visibility to progress, risks, interdependencies, and required decisions.
- Leadership team effectiveness and governance. Lead the operating rhythm for OMALT, including agendas, strategic reviews, offsites, decision governance, action tracking, and accountability mechanisms. Continuously improve leadership team processes to focus time on the highest-value priorities and strengthen collaboration and execution.
- Cross-functional integration and strategic initiatives. Lead or coordinate high-priority business and organizational initiatives on behalf of the Chief Oncology Medical Officer. Build strong partnerships across global, regional, and country Medical Affairs and with Oncology, Research, Development, Commercial, People Experience, Finance, Communications, and other enabling functions to align stakeholders and deliver outcomes.
- Resource and FTE management. Coordinate resource and full-time equivalent (FTE) planning across Oncology Medical Affairs, helping leaders assess capacity, capabilities, trade-offs, and deployment against strategic priorities. Maintain visibility to resource needs and support disciplined prioritization and organizational decision-making.
- Organizational effectiveness, culture, and talent. Partner with People Experience and leaders to advance workforce and talent planning, succession, leadership development, colleague engagement, onboarding, leadership transitions, and organizational effectiveness. Help foster a culture of inclusion, accountability, collaboration, innovation, and continuous improvement.
- Communications and stakeholder engagement. Develop a strong understanding of Pfizer Oncology strategy, Medical Affairs priorities, evidence-generation activities, and organizational capabilities. Partner with Communications to develop executive presentations, briefing materials, talking points, town halls, organizational updates, site visits, and other internal and external engagements that strengthen clarity, alignment, and confidence.
- AI-enabled ways of working and operational excellence. Understand, embrace, and regularly use artificial intelligence (AI), digital tools, and advanced analytics to improve planning, insight generation, communications, decision support, and operational efficiency. Promote responsible adoption of AI-enabled ways of working in alignment with Pfizer policies and applicable requirements, while identifying opportunities to simplify processes and improve organizational impact.
BASIC QUALIFICATIONS
- Bachelor's degree with 12+ years of relevant experience; or master's degree, MBA, MPH, PharmD, or equivalent with 10+ years of relevant experience; or PhD with 7+ years of relevant experience.
- Relevant experience in the biopharmaceutical industry, healthcare, Medical Affairs, R&D operations, business operations, strategy, or a related field.
- Demonstrated experience leading complex, cross-functional initiatives and delivering results in a global, highly matrixed organization.
- Strong business planning, operational leadership, project and portfolio management, organizational effectiveness, and stakeholder management capabilities.
- Exceptional written, verbal, presentation, and executive communication skills, with the judgment and discretion required to work with senior leaders and sensitive information.
- Proven ability to influence without direct authority, manage competing priorities, and convert ambiguous or complex objectives into clear plans, decisions, and measurable outcomes.
- Demonstrated proficiency using AI and digital productivity tools regularly and responsibly to improve the quality, speed, and effectiveness of work.
PREFERRED QUALIFICATIONS
- Oncology or Medical Affairs experience and an understanding of evidence generation, scientific communications, patient-centered medical strategy, and the healthcare ecosystem.
- Experience in a Business Operations, Development Business Operations (DBO), strategy, program leadership, or organizational effectiveness role supporting a senior executive or leadership team.
- Experience with FTE planning, workforce capacity management, resource allocation, and organizational prioritization.
- Experience leading organizational change, business transformation, capability building, or leadership team effectiveness initiatives.
- Demonstrated ability to apply AI, advanced analytics, and digital tools to business operations, decision support, communications, or process improvement.
- Experience leading and developing colleagues or teams, including resources operating through matrix relationships.
- Strong business acumen, executive presence, sound judgment, organizational maturity, and the ability to build trusted relationships across internal and external stakeholders.
The annual base salary for this position ranges from $214,900.00 to $358,100.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 22.5% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.

This role is posted in multiple locations. If you are applying for the role in an secondary job posting location where pay transparency regulations apply, your Talent Advisor will share the local pay information with you during the first interview.


Relocation assistance may be available based on business needs and/or eligibility.
Candidates must be authorized to be employed in the U.S. by any employer.
U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.
Sunshine Act
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EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
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Bus Dev & Strategic Planning
