Histotechnologist

About you:

You’re a skilled bench histologist who takes pride in producing high-quality sections and stains. You’re comfortable working independently, juggling requests from multiple teams, and building workflows from scratch. You’re organized, detail-oriented, and proactive - the kind of person who keeps a lab running smoothly without being asked. You communicate clearly with scientists, understand what they need from their tissue, and can advise on best practices from fixation through imaging.

What you'll do in this role:

Support day-to-day histology operations by independently executing workflows - managing work prioritization, quality control, and turnaround timelines 

Partner with the histology lead and scientific teams to triage and schedule work across programs, communicating realistic timelines, flagging conflicts early, tracking sample throughput, and maintaining organized records

Perform tissue and organoid embedding, paraffin and frozen sectioning, vibratome sectioning, and slide preparation for multiple scientific teams

Conduct IHC and IF staining, including protocol optimization and new antibody validation

Perform H&E staining and special stains as needed

Support the development and documentation of  SOPs for histology workflows, continuing to build the institutional knowledge for Retro’s histology practice 

Operate and maintain standard histology equipment - embedding center, microtome, cryostat, vibratome, water baths, fume hood, and associated instruments

Coordinate with CROs for tissue processing and ensure quality of incoming processed tissues

Decalcify tissues as needed for bone or calcified samples

Assist with imaging of stained sections or coordinate with instrument engineers for imaging support

Manage histology supplies inventory, ordering, and lab organization

Provide guidance to scientists on tissue collection, fixation, and handling best practices to ensure downstream quality

You might thrive in this role if you:

Have 5+ years of hands-on histology experience with FFPE and fresh-frozen workflows - embedding, microtomy, and staining

Are proficient with both paraffin sectioning and cryosectioning

Have experience with IHC and/or IF staining, including antibody titration and protocol troubleshooting

Have demonstrated ability to work independently and manage multiple concurrent requests

Are naturally organized and detail-oriented - you keep clean records and a clean lab

Communicate clearly and effectively - whether discussing tissue orientation with a scientist or coordinating things

Are hands-on and proactive - you don’t wait to be told when something needs to be done

Bonus if you have experience with:

Multiplex staining techniques 

Start-up experience or more resource-constrained environments

GLP or regulated laboratory environments