Principal Instrumentation Technician

Location: Vacaville, California

This is a fully site‑based role. Working together in person supports close, real‑time collaboration and the technical precision needed to manufacture medicines to the highest quality and safety standards.

The Principal Instrumentation Technician will function as a liaison between Instrument Services, MSAT, and Reliability Engineering, troubleshoot highly complex issues, provide oversight and guidance, mentor, and create necessary training to ensure a broad base of knowledge within the Instrument Services group. In addition, this individual will participate in the Maintenance Optimization team as an SME to drive improvements that will enable less equipment downtime, eliminate waste, and develop integrated technological solutions.

What you will get:

The full-time base annual salary for this position is expected to range between $78,750 to $131,250.  In addition, below you will find a comprehensive summary of the benefits package we offer:

• Performance-related bonus
• Medical, dental and vision insurance
• 401(k) matching plan
• Life insurance, as well as short-term and long-term disability insurance
• Employee assistance programs
• Paid Time Off 

Shift: Tuesday -Friday 4x10's, Swing shift.

 What you will do:

• Provide advanced hands-on troubleshooting for highly complex instrumentation and mechanical equipment failures, resolving out-of-tolerance conditions to optimize, validate, and restore production uptime.
• Serve as the Instrument Services SME on the Maintenance Optimization team and participate in cross-functional governance teams to advise on equipment design, procurement, commissioning, and qualification.
• Partner with Production, MSAT, and Reliability Engineering to identify and lead continuous improvement initiatives focused on enhancing safety, quality, and cost efficiency across site operations.
• Conduct root cause assessments for process discrepancies and Quality investigations using systems like Track Wise/Veeva; implement corrective actions and initiate necessary maintenance documentation updates.
• Identify and implement equipment and procedural improvements within the Preventive Maintenance program to ensure strict alignment with cGMP standards and regulatory requirements.
• Act as a team lead to coordinate work, exercise independent judgment on critical site tasks, and design and deliver continuing technical education to upskill maintenance staff.
• Perform active in-process and post-completion field audits to enforce quality execution, verify adherence to maintenance procedures, and prevent rework.

What we look for:

• High School Diploma.
• 5+ years of relevant experience in a GMP environment.
• 5 to 10 years in manufacturing process instrumentation, control systems, or analytical instrumentation preferred.
• Strong understanding of industrial process instrumentation principles and systems.
• Ability to lift up to 50 lbs with reasonable accommodations.
• Valid driver’s license.

About Lonza

At Lonza, our people are our greatest strength. With 30+ sites across five continents, our globally connected teams work together every day to manufacture the medicines of tomorrow. Our core values of Collaboration, Accountability, Excellence, Passion and Integrity reflect who we are and how we work together. Everyone’s ideas, big or small, have the potential to improve millions of lives, and that’s the kind of work we want you to be part of.

Innovation thrives when people from all backgrounds bring their unique perspectives to the table. At Lonza, we offer equal employment opportunities to all qualified applicants regardless of race, religion, color, national origin, sex, sexual orientation, gender identity, age, disability, veteran status, or any other characteristic protected by law.

Ready to shape the future of life sciences? Apply now.