USA - New Jersey - Rahway, United States of America
Onsite
Job Description
Primary Responsibilities:
In the Development Sciences and Clinical Supply (DSCS) organization, we believe digital is the force multiplier that enables faster experiments, smarter decisions, more robust supply chains, and is ultimately redefining how we bring medicines to patients.
Within DSCS, the DSCS Digital Technologies (DDT) team is building the next generation of data-rich, connected lab environments— where hardware, software, and AI-driven tools work together to accelerate pharmaceutical development. Our goal is simple but ambitious: embed advanced digital capabilities into the DNA of how we work. We believe this future starts with a strong foundation of laboratory tools: innovative robotics, process analytical technology (PAT), high-throughput technologies, reliable instrumentation, and integrated systems that seamlessly contextualize data and transition it from the physical labs to the digital world. Our innovation is fueled by diverse teams coming together to build technologies that truly impact how our scientists conduct research. We’re looking for a Principal Scientist to help realize this vision.
In this role, the chosen candidate will work with a team of scientists tasked with identifying, developing, and deploying digital and data-rich technologies aimed at improving Process, Product, and Analytical understanding. The tools that we develop are as diverse as the team developing them, and in this role, the chosen candidate will leverage digital technologies to enable chemistry, manufacturing, and controls (CMC) activities across our small molecule, biologics, and vaccines portfolio.
This role will focus on developing and applying ontology-driven and semantic technologies that transform complex scientific information into structured, contextualized, and reusable knowledge. This includes leveraging knowledge representation, semantic enrichment, metadata strategies, and scientific data integration approaches to connect laboratory systems, instruments, data platforms, and scientific workflows. The successful candidate will help establish the semantic foundation that supports next-generation digital laboratories, AI-enabled scientific workflows, and connected pharmaceutical development.
Working at the intersection of pharmaceutical science, digital technologies, and data integration, the candidate will support the development of semantic models, ontologies, and knowledge graph frameworks that improve interoperability, traceability, discoverability, and consistency across scientific systems. Through these efforts, the candidate will help enable FAIR, AI-ready scientific data ecosystems that accelerate research, enhance decision making, and improve the way scientific knowledge is generated, managed, and reused across the development lifecycle.
One of the most unique aspects of this role is the opportunity to work directly with scientists developing biologics, vaccines, and small molecules while helping build the semantic and digital foundations that power next-generation pharmaceutical development. Rather than operating as a traditional informatics or IT function, this role is deeply embedded within scientific research and development, ensuring that emerging digital and semantic capabilities create meaningful impact for laboratory scientists and development teams.
How You’ll Make an Impact
Education Minimum Requirement:
Required Experience and Skills:
Preferred Experience and Skills:
Required Skills:
Adaptability, Adaptability, Animal Vaccination, Cell Culture Process Development, Cell Line Development, Combination Products, Computer Science, Data Analysis, Data Engineering, Drug Development, Finite Element Analysis (FEA), Innovative Thinking, Laboratory Automation, Leadership Mentoring, Materials Science, Oncology, Ontology Development, Pharmaceutical Development, Pharmaceutical Process Development, Pharmaceutical Sciences, Professional Collaboration, Professional Networking, Quality by Design, Regulatory Filings, Scientific Data Management {+ 2 more}Preferred Skills:
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US and Puerto Rico Residents Only:
Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.
As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics. As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:
We are proud to be a company that embraces the value of bringing together, talented, and committed people with diverse experiences, perspectives, skills and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas, broad experiences, backgrounds, and skills come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively.
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The salary range for this role is
$173,200.00 - $272,600.00This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employee’s position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs.
The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.
We offer a comprehensive package of benefits. Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at https://jobs.merck.com/us/en/compensation-and-benefits.
You can apply for this role through https://jobs.merck.com/us/en (or via the Workday Jobs Hub if you are a current employee). The application deadline for this position is stated on this posting.
San Francisco Residents Only: We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance
Los Angeles Residents Only: We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles’ Fair Chance Initiative for Hiring Ordinance
Search Firm Representatives Please Read Carefully
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.
Employee Status:
RegularRelocation:
VISA Sponsorship:
Travel Requirements:
Flexible Work Arrangements:
HybridShift:
Valid Driving License:
Hazardous Material(s):
Job Posting End Date:
08/9/2026*A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.
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