Job Description Summary
Position Location: onsite, Cambridge, MA
Job Description
Key Responsibilities:
Drive scientific activities supporting the discovery and optimization of next-generation xDC and biologics platforms
Contribute to the design and evaluation of new vectorization approaches for targeted delivery
Support the development of payload strategies aligned with disease biology and therapeutic mechanism of action
Participate in the exploration of differentiated conjugate formats, including multi-payload or combination-based approaches
Work closely with cross-functional teams across biology, chemistry, protein engineering, pharmacology, translational sciences, and CMC
Design, execute, and interpret experiments to guide platform and program decisions.
Identify emerging scientific opportunities and help translate them into actionable research strategies
Communicate results clearly through presentations, reports, and scientific discussions
Contribute to external collaborations and technology evaluation efforts as needed
Maintain awareness of the competitive and scientific landscape in ADCs, biologics, and targeted therapeutic platforms
Essential Requirements:
Ph.D. in biology, biochemistry, molecular biology, pharmacology, immunology, chemical biology, bioengineering, or a related discipline
3–5 years of relevant post-Ph.D. experience, preferably in an industry setting
Experience with biologics, antibody-drug conjugates, targeted delivery platforms, protein therapeutics, or related modalities
Strong understanding of disease biology, target selection, mechanism-of-action studies, and translational research principles
Familiarity with biologics engineering, conjugation strategies, payload biology, or preclinical therapeutic development is preferred
Demonstrated ability to design rigorous experiments, analyze complex data, and make data-driven recommendations
Strong communication, collaboration, and problem-solving skills
Ability to work effectively in a fast-paced, multidisciplinary research environment
Preferred Experience:
Prior experience in ADC, xDC, or other targeted therapeutic platforms
Experience evaluating novel targets, payload mechanisms, or biology-driven therapeutic hypotheses
Familiarity with in vitro and in vivo pharmacology workflows
Experience working with external partners, CROs, academic collaborators, or technology vendors
Track record of scientific contributions through publications, patents, presentations, or program advancement
The salary for this position is expected to range between $119,700 and $222,300 per year. The final salary offered is determined based on factors like, but not limited to, relevant skills and experience, and upon joining Novartis will be reviewed periodically. Novartis may change the published salary range based on company and market factors.
Your compensation will include a performance-based cash incentive and, depending on the level of the role, eligibility to be considered for annual equity awards.
US-based eligible employees will receive a comprehensive benefits package that includes health, life and disability benefits, a 401(k) with company contribution and match, and a variety of other benefits. In addition, employees are eligible for a generous time off package including vacation, personal days, holidays and other leaves.
To learn more about the culture, rewards and benefits we offer our people click here.
EEO Statement:
The Novartis Group of Companies are Equal Opportunity Employers. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, sex, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status.
Accessibility and reasonable accommodations
The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or to perform the essential functions of a position, please send an e-mail to us.reasonableaccommodations@novartis.com or call +1(877)395-2339 and let us know the nature of your request and your contact information. Please include the job requisition number in your message.
Salary Range
$119,700.00 - $222,300.00
Skills Desired
Analytical Thinking, Chemical Biology, Chemistry, Clinical Trials, Collaboration, Curious Mindset, Data Analysis, Detail-Oriented, Drug Development, Ethics, Gene Therapy, Immunology, Inventory Management, Machine Learning (ML), Medical Research, Molecular Biology, Python (Programming Language), Science