Research Associate, Genome Engineering

An affiliate of Colossal is looking for a talented Research Associate with knowledge and passion for ambitious synthetic biology projects and large-scale genome engineering for species conservation and de-extinction. We will be building tools and methodologies for engineering various cell types, and will develop workflows to manipulate large DNA fragments and genomes. The candidate will work with a talented group of engineers and biologists committed to developing novel technologies that will change the world.

**This position will be based out of Dallas, TX. Relocation assistance is available**

Duties and Responsibilities:

• Work with senior lab members to support the design, development and testing of multiplex genome engineering tools in mammalian cells
• Perform routine molecular biology workflows, including plasmid DNA preparation (mini/midi/maxi preps), PCR, gel electrophoresis, and gel analysis
• Generate high-throughput assays for the buildout of gene editing workflows
• Assist with general lab operations, such as inventory management, preparation of common stocks, and basic equipment maintenance
• Work with team members to assess efficiency of genome editing through Sanger/NGS sequencing approaches
• Work on project milestones
• Attend lab meetings, prepare progress reports and presentations
• Great organizational skills and excellent laboratory record maintenance
• Learn new techniques as they become available or implemented within the company

Required Skills and Abilities:

• Hands-on experience in molecular biology (nucleic acid and protein extraction, gel electrophoresis) and cloning techniques (restriction enzyme-based cloning, Gibson assembly)
• Preferred experience with with PCR and flow cytometry
• Preferred experience with sequence analysis software (e.g., SnapGene, Geneious)
• Strong written and oral communication skills, as well as creative problem-solving skills.
• Preferred familiarity with electronic lab notebooks (ELN) and laboratory inventory management systems
• Preferred experience with mammalian cell culture

Education and Experience:

• Bachelor’s or Master’s degree in biological sciences, bioengineering, molecular biology, genetics, or any science related field.
• Prior hands-on research experience in academia or industry is highly desirable.