Scientist in Translational Pathology, Oncology 

Are you currently working in a clinical or hospital laboratory setting and looking to apply your pathology expertise to drive innovation in cancer research? Join AstraZeneca’s Translational Pathology group within our Oncology R&D Translational Medicine department and take your career beyond traditional healthcare environments. Be at the cutting edge of translational science, where your clinical insights will directly influence the development of life-changing cancer treatments.  

At AstraZeneca, we value your clinical experience and understand the critical role of laboratory experts from the hospital and NHS sectors in advancing precision oncology. Here, you’ll collaborate with scientific leaders from across the globe, applying your real-world expertise to projects with a direct impact on patient outcomes.  

What You’ll Do  

This is a lab-based position in a Good Clinical Practice (GCP) environment, designed for those who thrive in rigorous, quality-focused clinical or hospital laboratories.  

• Laboratory Operations: Deliver day-to-day laboratory activities that support translational pathology and biomarker programs, ensuring work is performed efficiently, accurately, and in accordance with approved procedures and compliance requirements.  

• GCP Compliance and Quality: Maintain and promote a strong quality culture within the laboratory by adhering to GCP, SOPs, documentation standards, sample traceability requirements, and data integrity principles.  

• Sample Management: Receive, track, process, store, and manage clinical and research specimens with a high degree of care and accuracy, ensuring chain of custody and sample integrity are maintained throughout.  

• Assay Support: Perform and support laboratory assays relevant to translational pathology and biomarker analysis, which may include tissue-based, histology, immunohistochemistry, digital pathology, molecular, or related translational laboratory techniques depending on laboratory scope.  

• Documentation and Data Handling: Accurately document laboratory activities, results, deviations, equipment records, and study-related information in compliance with regulatory and internal quality expectations.  

• Equipment and Laboratory Readiness: Support laboratory readiness through equipment maintenance, calibration coordination, reagent and consumable management, inventory oversight, and general laboratory organization.  

• Method and Process Improvement: Contribute to the implementation, optimization, validation, transfer, and continuous improvement of laboratory methods and operational workflows to enhance quality, reproducibility, and efficiency.  

• Cross-Functional Collaboration: Partner with biomarker scientists, translational researchers, pathologists, clinical study teams, quality representatives, and external collaborators to ensure laboratory activities align with project and study needs.  

• Inspection and Audit Support: Assist with preparation for audits and inspections and support responses to quality findings, CAPAs, and documentation reviews as needed.  

• Health, Safety, and Compliance: Work in accordance with all laboratory safety requirements, biosafety procedures, and applicable regulatory and company standards.  

What We’re Looking For  

• Education: Degree in Biomedical Science, Molecular Biology, Life Sciences, or a related scientific discipline.  

• Laboratory Experience: Hands-on experience working in a regulated or quality-controlled laboratory environment, ideally involving clinical samples, translational research, pathology, or biomarker analysis.  

• Regulated Environment Knowledge: Understanding of GCP, quality systems, documentation requirements, and the importance of traceability and data integrity in a laboratory setting.  

• Technical Skills: Practical experience in one or more relevant laboratory techniques, such as histology, immunohistochemistry, tissue handling, image analysis, molecular assays, or biomarker-related workflows.  

• Operational Mindset: Ability to manage competing priorities, maintain laboratory organization, and deliver consistent, high-quality output in a dynamic environment.  

• Communication and Teamwork: Strong written and verbal communication skills with the ability to work effectively across multidisciplinary teams.  

• Attention to Detail: High level of accuracy in laboratory execution, documentation, and record keeping.  

Why Transition to AstraZeneca?  

Bring your patient-centred perspective into the heart of oncology research. This is your opportunity to move beyond diagnostics and play a pivotal role in translational medicine, accelerating the impact of your clinical skills to benefit patients worldwide. Discover a rewarding career path where your hospital or clinical laboratory experience is not just valued—it’s essential.  

Next Steps - If you are ready to translate your clinical expertise into pioneering science, apply today! Join us in delivering the next generation of cancer therapies.