Job Description
The Quantitative Biosciences Department at our Company's Research Laboratories is seeking a highly motivated Scientist to join our In-Vivo Pharmacology group at our Research Labs in Boston. The successful candidate will be responsible for developing disease models, planning / designing and execution of in-vivo pharmacologic or mechanistic studies using disease models, collection / analysis of data, and report writing in support of research & development programs in immunology and oncology therapeutic areas.
Primary Responsibilities:
Plan, design and execute in-vivo pharmacological experiments to support and advance drug discovery programs in immunology and oncology.
Characterize and optimize in vitro, ex vivo or in vivo assays at scale to support potential compound screening, biomarker identification and mechanism of action studies.
Run validation and research operating plan (ROP) assays for test articles with appropriate benchmarks.
Maintain timely, accurate laboratory records of activities & comply with good documentation practices.
Effectively collaborate with integrated teams in a matrix organization setting to facilitate the conduct of studies and to the success of discovery programs.
Education Minimum Requirements:
M.S. in Immunology, Pharmacology, Biology, Biotechnology, Molecular and Cell Biology, Biochemistry, Bioengineering,
or related STEM field with 1+ year of relevant postgraduate experience or B.S. with 3+ years of relevant post-graduate in-vivo experience, preferably in a pharmaceutical/ research laboratory setting
Required Experience and Skills:
Hands-on experience with in-vivo models – particularly related to autoimmune disease or tumor immunology.
Experience in PK/PD models, autoimmune/tumor efficacy experience.
ELISA, Western blot, and flow cytometry and other immunological assay skills are desired.
Working knowledge using standard data analysis tools such as Graph Pad Prism, FlowJo, etc., and Microsoft programs.
Excellent written and interpersonal communication skills and the ability to collate the results and make a presentation to the stakeholders.
The ability to work independently, as well as collaboratively with peers within and across departments is expected.
#EligibleforERP
Required Skills:
Assay, Autoimmune Diseases, Cell-Based Assays, Drug Discovery Process, Flow Cytometry, Immunoassays, Immunology, Inflammatory Diseases, In Vivo Pharmacology, Mouse Handling, Mouse Models, Oncology, Tumor ModelsPreferred Skills:
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The salary range for this role is
$98,000.00 - $154,300.00This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employee’s position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs.
The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.
We offer a comprehensive package of benefits. Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at https://jobs.merck.com/us/en/compensation-and-benefits.
You can apply for this role through https://jobs.merck.com/us/en (or via the Workday Jobs Hub if you are a current employee). The application deadline for this position is stated on this posting.
San Francisco Residents Only: We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance
Los Angeles Residents Only: We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles’ Fair Chance Initiative for Hiring Ordinance
Search Firm Representatives Please Read Carefully
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.
Employee Status:
RegularRelocation:
DomesticVISA Sponsorship:
NoTravel Requirements:
No Travel RequiredFlexible Work Arrangements:
Not ApplicableShift:
Not IndicatedValid Driving License:
NoHazardous Material(s):
Bloodborne pathogens, BSL2, OEB4, OEB5, standard lab reagentsJob Posting End Date:
06/4/2026*A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.