Senior Clinical Scientist - Oncology - Home Based

Accountabilities

• Lead or support one or more oncology clinical studies, depending on study size and complexity, ensuring scientific integrity and appropriate execution of study protocols.

• Serve as the primary clinical and scientific contact for internal and external stakeholders, addressing scientific questions and supporting interactions with investigators, study sites, and ethics committees or institutional review boards.

• Contribute to clinical trial design and endpoint development in collaboration with clinical development leadership.

• Lead medical monitoring activities, including developing Medical Monitoring Plans, reviewing serious adverse event (SAE) reports, and supporting safety assessments.

• Establish and support Safety Advisory Committees, Data Monitoring Committees, adjudication committees, and other relevant study oversight groups.

• Collaborate with medical writers on protocol development and amendments, participate in governance reviews, prepare protocol clarification letters, and contribute to study-specific documentation.

• Review and update informed consent documents and provide scientific input into data management deliverables, including electronic data capture systems, data review plans, and case report forms.

• Monitor clinical data issues requiring scientific input, review central laboratory reports and external data, and identify safety concerns or clinically significant values.

• Prepare scientific presentations and slides, participate in investigator meetings, and communicate protocol requirements and scientific information to study teams.

• Act as the scientific lead within the Clinical Trial Team (CTT), collaborating with study management, medical writing, and other functions to achieve study milestones.

• Review study specifications, initiate randomization and allocation requests, and coordinate relevant approval schedules and allocation system requirements.

• Coordinate laboratory requirements, biological specimen handling, and imaging specifications to ensure alignment with study protocols.

• Contribute to study newsletters, database lock activities, Clinical Study Reports (CSRs), regulatory submission documents, and other clinical development deliverables.

• Review and reconcile protocol deviation classifications, prepare deviation listings for clinical study reports, and support consistent documentation of study compliance.

• Collaborate with medical writing teams on communicating trial results to investigators and support scientific publications and presentations as needed.

• Provide scientific input for operational reviews, support interactions with external vendors, and supply clinical specifications for systems such as interactive voice response systems (IVRS) and electronic patient-reported outcomes (ePRO).

• Mentor other Clinical Scientists and provide additional support to study management and medical writing teams to ensure timely, high-quality deliverables.

Requirements

• Educational background and clinical research experience:

  • Bachelor's degree in Life Sciences or a related discipline, with at least seven years of clinical research experience.

  • Alternatively, a Master's degree or PhD in Life Sciences, with at least five years of clinical research experience.

  • Candidates without a Life Sciences degree must have significant clinical development experience, typically exceeding 11 years.

  • At least two years of pharmaceutical or clinical drug development experience working as a lead Clinical Scientist.

  • Demonstrated experience in medical monitoring, including the review and assessment of clinical safety information.

  • Strong oncology clinical research experience and a solid understanding of oncology trials and their scientific requirements.

  • Excellent proficiency in Microsoft Excel and PowerPoint for data review, analysis, and scientific presentations.

  • Strong written and verbal communication skills, with the ability to present complex scientific information clearly to diverse audiences.

  • Ability to collaborate effectively with multidisciplinary teams, investigators, medical writers, study managers, and external stakeholders.

  • Strong analytical thinking, attention to detail, scientific judgment, and organizational skills.

  • Ability to manage multiple study deliverables and priorities while maintaining scientific quality and compliance.

  • Willingness and ability to travel up to 15% of the time, potentially including international travel.

  • Must be legally authorized to work in Canada for a Canada-based position and must not require current or future employer sponsorship for an employment visa.

  Benefits

  • Competitive compensation: Competitive base salary, with performance-related incentive opportunities.

  • Health coverage: Medical, dental, and vision benefits, where applicable.

  • Retirement benefits: Access to retirement savings and pension plans, depending on location and eligibility.

  • Financial protection: Life assurance and disability coverage.

  • Employee well-being: Employee assistance programmes and resources supporting personal and professional well-being.

  • Professional development: Structured training, ongoing learning opportunities, and career development pathways.

  • Remote work arrangement: Home-based work for eligible candidates in Canada.

  • Collaborative environment: Opportunity to work with multidisciplinary clinical research professionals in a sponsor-dedicated model.

  • Meaningful scientific impact: Contribute to oncology clinical trials and the development of treatments that may improve patient outcomes worldwide.