Senior Manager, Evidence & Insights (RWE & HEOR)

Real Chemistry is looking for an Senior Manager join our growing Evidence & Insights team! 

The Senior Manager, Evidence & Insights provides strategic and scientific support across real-world evidence (RWE), health economics and outcomes research (HEOR), and evidence generation. This role co-leads client engagements end-to-end, helping to shape evidence strategies, oversee analytics and deliverables, and advise biopharma and related stakeholders. 

This is a hybrid role, based in any of our US offices—including New York City, Boston, Chicago, Indianapolis, or San Francisco—or remotely within the US, depending on team and business needs.

What you'll do: 

• Co-lead and support RWE and HEOR strategy across client programs, including evidence planning, study design, and interpretation of findings to inform value, access, and payer and health system decision-making. 
• Design and support evidence generation plans (e.g., RWE studies, retrospective database studies, economic models) aligned to product lifecycle needs and client requirements. 
• Develop and oversee the process for systematic literature reviews (SLRs), including the development of study protocols, execution of study searches, delegation of screening, and oversight of data extraction and reporting (leveraging the Nested Knowledge platform where possible).
• Translate complex real-world datasets and outcomes evidence into clear, defensible insights and recommendations for clients (clinical, economic, and utilization outcomes). 
• Serve as a client co-lead alongside Director and VP: build trusted relationships, guide strategic direction, and ensure work products meet scientific rigor, timelines, and client expectations. 
• Directly manage staff planning, internal and external project timelines, internal and external communications, and budgets to ensure projects are adequately staffed, managed, and executed.
• Stay current on evolving evidence standards and trends impacting access decisions, including: 
  • HTA requirements and value frameworks 
  • Payer evidence expectations and comparative effectiveness 
  • RWE guidance and regulatory considerations 
  • Measurement/reporting of quality, performance, and outcomes 
• Co-lead scoping and resourcing for engagements: define scope of work, timelines, budgets, and staffing plans; proactively manage risks and changes. 
• Partner cross-functionally to connect evidence strategy to broader client objectives and account growth. 

This position is a perfect fit for you if:

• You are adaptable, resilient, and OK with adjusting your scope, responsibilities, and focus as we grow. When things change, so do we. We’re always evolving.
• You are proactive, driven, and resourceful with strong prioritization skills and a desire to dive into the data.
• You are highly organized self-starter, able to work independently and under tight deadlines. 

What you should have: 

• 3-5+ years of relevant experience in HEOR, RWE, SLR, epidemiology, outcomes research, market access strategy, or closely related fields (consulting and/or biopharma experience preferred). 
• Bachelor’s degree required; advanced degree strongly preferred (MPH, PhD, PharmD, MD, MS, or equivalent) in health economics, epidemiology, public health, biostatistics, health services research, or related discipline. 
• Demonstrated expertise in HEOR/RWE study design and execution and ability to translate evidence into access-relevant strategy. 
• Strong project/program leadership experience, including managing teams on complex, multi-workstream engagements and ensuring scientific and editorial quality. 
• Excellent writing, editing, and executive communication skills; ability to craft clear narratives from technical analyses. 
• Strong analytical fluency and comfort engaging with complex datasets and statistical outputs (hands-on analytics not required but highly valued). 
• Client-service orientation, sound judgment, high attention to detail, and ability to operate effectively in a fast-paced environment. 
• Proficiency with Microsoft Office (PowerPoint, Excel, Word, Outlook). 

 Pay Range: $90,000-$110,000

This is the pay range the Company believes it will pay for this position at the time of this posting.  Consistent with applicable law, compensation will be determined based on job-related, non-discriminatory factors including but not limited to work experience, skills, certifications, and geographical location. The Company reserves the right to modify this pay range at any time.