Onsite
Use Your Power for Purpose
At the heart of Pfizer's Digital transformation sits Infrastructure & Cloud, enabling modern cloud infrastructure and engineering capabilities that influence business outcomes and provide value to our business, shareholders, and patients every day.
Pfizer is seeking an execution-focused Senior Director to lead transformational cloud and infrastructure initiatives that directly enable breakthrough science and drug discovery. You'll play a critical leadership role in developing our next-generation cloud platform for AI/ML-powered research while building and leading a high-performing technical team.
This role combines strategic thinking with hands-on delivery, technical depth with leadership impact, and the autonomy to make decisions that advance Pfizer's mission. Your work will provide the infrastructure foundation that enables our scientists to accelerate research, analyze complex data, and develop treatments that improve patients' lives.
Pfizer seeks individuals that are highly self-motivated, eager to learn, and effective when working in a team environment. A strong aptitude towards self-development, continuous learning, and growth is highly desired.
What You Will Achieve
The Senior Director, Cloud and Infrastructure Transformation provides executive-level technical leadership and strategic direction, playing a critical role in ensuring Pfizer continues to leverage cloud-native design patterns and modern infrastructure practices at enterprise scale. This role will help ensure our Infrastructure & Cloud organization delivers secure, compliant, productive, and innovative platforms that enable breakthrough science.
You will lead a team of 3-5 Directors and Senior Managers and Directors, providing strategic guidance, mentorship, and support in their professional development while driving the adoption of transformational cloud and infrastructure initiatives across the organization.
Lead enterprise cloud and infrastructure transformation, including AI/ML platforms, data center migration, and network transformation
Drive multi‑cloud, data center, and network initiatives with strong execution
Make high‑impact architectural and technology decisions
Provide senior technical leadership and shape infrastructure strategy
Lead and develop senior leaders and high‑performing teams
Partner with security, digital, and business stakeholders
Operate effectively in a global, matrixed organization
Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.
Here Is What You Need (Minimum Requirements):
Bachelor’s degree in information technology, Computer Science, Computer Engineering, or a similar discipline
12+ years in infrastructure, cloud, and networking with proven track record of delivering complex, multi-year transformation programs
Deep multi-cloud expertise (AWS, Azure, GCP) with hands-on experience building production platforms at scale
Comprehensive understanding of the full stack from on-premises data centers to cloud-native architectures
Demonstrated success managing and developing senior technical leaders (Senior Managers, Directors)
Extensive experience leading through influence in matrixed organizations, working across technical and business stakeholders
Strong technical judgment shaped by real-world experience delivering at scale - hands-on when needed, strategic enough to delegate and orchestrate
Expertise in modern cloud-native architectures, IaC (Terraform/OpenTofu), DevOps practices, automation, and security/compliance in regulated industries
Excellent communicator with the ability to translate technical complexity for diverse audiences and drive alignment
Proven ability to deliver results while managing multiple complex initiatives simultaneously
Pragmatic decision-maker who balances ideal solutions with practical constraints and knows when to seek input or escalate
Bonus Points If You Have (Preferred Qualifications):
AI/ML infrastructure experience, especially supporting research and data science workloads
Background in pharma, biotech, or highly regulated industries
Cloud certifications demonstrating depth of expertise
Experience with large-scale migrations, datacenter exits, or M&A integrations
Global team management across time zones and cultures
Other Job Details
Last day to apply: May 28, 2026
Work location assignment: Hybrid - onsite at NY Headquarters an average of 2.5 days per week or as the business requires
10-20% Travel
Relocation assistance may be available based on business needs and/or eligibility.

Candidates must be authorized to be employed in the U.S. by any employer.
U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.

Sunshine Act
Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.
EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
Pfizer endeavors to make www.pfizer.com/careers accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email disabilityrecruitment@pfizer.com. This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned.
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