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New York, New York, United States
Hybrid
Use Your Power for Purpose
At the heart of Pfizer's Digital transformation sits Infrastructure & Cloud, enabling modern cloud platforms and engineering capabilities that accelerate scientific discovery, empower researchers, and improve patient outcomes worldwide.
Pfizer is seeking a highly accomplished technology leader who combines enterprise-scale strategic thinking with deep technical expertise in cloud, infrastructure, networking, and platform engineering. This role will shape the future of Pfizer's cloud and infrastructure ecosystem, enabling AI/ML-powered research, advanced analytics, and next-generation digital capabilities that support breakthrough science and drug discovery.
The successful candidate will be equally comfortable discussing business strategy with executive leadership, guiding large-scale transformation initiatives, and engaging directly with architects and engineers on critical technical decisions. This is a leadership role for someone who has not only led transformation programs but has personally helped design, build, and scale modern cloud platforms and infrastructure capabilities.
At Pfizer, your work will directly contribute to the technologies that enable scientists to accelerate research, unlock insights from complex data, and develop innovative medicines for patients around the world.
Pfizer seeks individuals who are highly self-motivated, intellectually curious, collaborative, and committed to continuous learning and growth.
What You Will Achieve
The Senior Director, Cloud & Infrastructure Transformation serves as both a strategic technology executive and a technical thought leader for Pfizer's cloud and infrastructure landscape. This leader will define future-state infrastructure strategy while ensuring the successful execution of complex, enterprise-scale initiatives spanning cloud, networking, data center modernization, platform engineering, and AI infrastructure.
You will lead a team of senior leaders, architects, and engineering organizations while helping establish the technology vision, engineering standards, and operating models required to support Pfizer's digital future.
You will be expected to drive business outcomes through technology strategy while maintaining the technical depth and credibility necessary to guide architecture decisions, challenge assumptions, and ensure engineering excellence.
Key Responsibilities
Leadership Expectations
Candidates should demonstrate a breadth of leadership experiences and capabilities, including:
Here Is What You Need (Minimum Requirements)
Preferred Qualifications
Ideal Candidate Profile
The ideal candidate is a technology strategist and engineer at heart. They have built credibility through hands-on technical leadership, can engage deeply in architectural discussions, and have successfully led large-scale transformation efforts that delivered measurable business value. They are equally effective influencing executive stakeholders, mentoring technical leaders, and driving execution across complex enterprise environments.
Most importantly, this leader brings both the strategic mindset to shape Pfizer's future and the technical depth to help build it.
Other Job Details
Last day to apply: 9/7/2026
Work location assignment: Hybrid - onsite at NY Headquarters an average of 2.5 days per week or as the business requires
10-20% Travel
Relocation assistance may be available based on business needs and/or eligibility.

Candidates must be authorized to be employed in the U.S. by any employer.
U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.

Sunshine Act
Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.
EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
Pfizer endeavors to make www.pfizer.com/careers accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email disabilityrecruitment@pfizer.com. This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned.
To learn more about acceptable and prohibited uses of AI during the recruitment process, please review our candidate AI-use guidelines available on Pfizer Careers.

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