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San Diego, California, United States
Onsite
Neurocrine Biosciences is a leading biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs. We are dedicated to discovering, developing and commercializing life-changing treatments for patients with under-addressed neurological, psychiatric, endocrine and immunological disorders. The company's diverse portfolio includes FDA-approved treatments for tardive dyskinesia, chorea associated with Huntington's disease, classic congenital adrenal hyperplasia, hyperphagia in patients with Prader-Willi syndrome, endometriosis* and uterine fibroids*, as well as a robust pipeline including multiple compounds in mid- to late-phase clinical development across our core therapeutic areas. For more than three decades, we have applied our unique insight into neuroscience and the interconnections between brain and body systems to treat complex conditions. We relentlessly pursue medicines to ease the burden of debilitating diseases and disorders, because you deserve brave science. For more information, visit neurocrine.com, and follow the company on LinkedIn, X, Facebook and YouTube. (*in collaboration with AbbVie)
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Leads development and execution of enterprise portfolio strategy, prioritization, and optimization frameworks aligned with corporate and R&D objectives
Owns and manages Neurocrine's multi-year compound flow model, including risk-adjusted and non-risk-adjusted portfolio scenarios across therapeutic areas and development stages
Develops and maintains transition probability models across development stages and modalities to support portfolio forecasting, investment planning, and strategic decision-making
Leads executive-level portfolio prioritization and trade-off discussions, translating complex portfolio data into actionable recommendations that support portfolio investment and resource allocation decisions
Evaluates portfolio opportunities, risks, development scenarios, and investment alternatives to maximize overall portfolio value
Designs and oversees quantitative models supporting portfolio forecasting, probability of success analyses, development timelines, resource planning, and investment decision-making
Develops scenario analyses evaluating the impact of adding, removing, accelerating, delaying, or restructuring portfolio programs
Analyzes pipeline progression, development productivity, attrition rates, cycle times, and key portfolio performance indicators to support strategic planning and governance discussions
Leads enterprise resource planning and capacity forecasting activities across functions, therapeutic areas, and development stages.
Partners with Finance, Program Management, and functional leaders to align portfolio objectives with organizational capacity, budgetary constraints, and long-range planning assumptions
Develops portfolio-level financial models supporting annual operating plans, investment prioritization, resource planning, and budget forecasting activities
Identifies resource constraints, operational risks, and strategic opportunities and develops recommendations to optimize portfolio execution
Serves as business owner and subject matter expert for portfolio planning systems, including Planisware and related portfolio management platforms
Establishes portfolio data standards, governance processes, and analytics best practices to support high-quality portfolio decision-making
Drives implementation and continuous improvement of portfolio analytics tools, systems, reporting capabilities, and governance processes
Leads benchmarking initiatives evaluating development timelines, costs, resource models, productivity metrics, and industry best practices
Leverages AI-enabled tools, external data sources, and advanced analytics methodologies to enhance portfolio insights, forecasting accuracy, and competitive benchmarking capabilities
Develops executive dashboards, portfolio reviews, governance materials, and Board-level presentations
Provides analytical support for business development evaluations, external innovation opportunities, and strategic investment assessments
Leads cross-functional portfolio planning processes and governance forums to drive alignment, transparency, accountability, and execution excellence
Serves as a trusted advisor to executive leadership on portfolio strategy, prioritization, resource allocation, and long-term planning decisions
Provides leadership, coaching, and mentoring to team members and cross-functional partners
Other duties as assigned
BS/BA degree in Life Sciences, Business, Finance, Engineering, Data Analytics, Operations Research, or related discipline and 14+ years of relevant pharmaceutical, biotechnology, healthcare, consulting, portfolio management, strategy, or related industry experience OR
Master's degree in a related discipline and 12+ years of relevant experience OR
PhD, PharmD, MBA, or other advanced degree and 10+ years of relevant experience
Deep understanding of pharmaceutical drug development across discovery, preclinical, clinical, regulatory, and commercialization stages
Significant experience managing multi-year compound flow models and portfolio forecasting methodologies
Expert knowledge of portfolio strategy, portfolio management, resource planning, and investment decision-making frameworks
Extensive experience supporting portfolio governance processes and executive-level decision-making
Advanced experience with Planisware or comparable portfolio management and planning platforms
Experience implementing, managing, or optimizing portfolio planning systems, analytics capabilities, and governance processes
Strong understanding of portfolio valuation, probability of success modeling, scenario planning, forecasting techniques, and portfolio optimization methodologies
Experience leading enterprise portfolio planning and prioritization processes across complex, multi-asset development portfolios
Demonstrated success influencing senior leaders and facilitating executive-level portfolio prioritization, investment, and resource allocation decisions
Experience developing multi-year portfolio strategies and long-range planning scenarios aligned with organizational objectives
Experience supporting executive governance committees, portfolio review forums, and strategic planning processes
Strong understanding of R&D financial planning, budgeting, forecasting, and resource allocation processes
Experience leading portfolio benchmarking and competitive operational analyses
Experience preparing executive leadership and Board-level presentations and materials
Familiarity with AI-enabled analytics tools, advanced modeling techniques, and external benchmarking resources preferred
Ability to evaluate portfolio risks and opportunities and translate findings into strategic recommendations that influence organizational strategy and investment decisions
Strong strategic thinking, business acumen, and ability to integrate scientific, operational, financial, and portfolio considerations into decision-making
Exceptional communication, influence, stakeholder management, and relationship-building skills
Demonstrated ability to communicate complex analyses and strategic recommendations to diverse audiences, including senior executives
Strong analytical, critical thinking, problem-solving, and decision-making capabilities
Proven ability to lead through influence and achieve results within highly matrixed organizations
Demonstrated ability to develop innovative solutions to complex business challenges with significant organizational impact
Strong planning, prioritization, organizational, and project leadership skill
Ability to manage multiple competing priorities in a dynamic and evolving portfolio environment
Demonstrated ability to build partnerships and align stakeholders across functions and organizational levels
Strong attention to detail while maintaining an enterprise-wide perspective
Ability to mentor, coach, and develop others while fostering a culture of accountability and continuous improvement.
Advanced proficiency with portfolio management, business planning, analytics, forecasting, and reporting tools
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Neurocrine Biosciences is an EEO/Disability/Vets employer.
We are committed to building a workplace of belonging, respect, and empowerment, and we recognize there are a variety of ways to meet our requirements. We are looking for the best candidate for the job and encourage you to apply even if your experience or qualifications don’t line up to exactly what we have outlined in the job description.
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The annual base salary we reasonably expect to pay is $226,500.00-$309,000.00. Individual pay decisions depend on various factors, such as primary work location, complexity and responsibility of role, job duties/requirements, and relevant experience and skills. In addition, this position offers an annual bonus with a target of 35% of the earned base salary and eligibility to participate in our equity based long term incentive program. Benefits offered include a retirement savings plan (with company match), paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage in accordance with the terms and conditions of the applicable plans.