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Melbourne, Victoria, Australia
Onsite
CSL is seeking a two (2) highly motivated Associate Scientists to join the CSL Translational Research Immunology team and contribute to the development and evaluation of novel therapeutics. Based at our new facility in Melbourne, you will focus on advancing biologic therapies, including recombinant antibodies and other protein-based mediators to target and modulate specific cell types.
You will support developing, validating, and conducting in vitro and ex vivo assays, as well as evaluating therapeutic candidates using human samples. This is an exciting opportunity to work at the interface of discovery and translational science, helping to drive the development of next-generation therapies with the potential to improve patient outcomes.
Key Responsibilities
Reporting to the Associate Director and Head of Mechanistic Pharmacology, Translational Research Immunology, you will:
Investigate biology of novel targets and the mechanism of action of potential therapeutic candidates.
Develop and perform multi-colour flow cytometry to phenotypically characterise immune cell subsets.
Develop and conduct functional assays to assess leukocyte effector functions, including activation, proliferation, cytokine production, cell signalling and cell death.
Develop and perform in vitro screening assays to identify potential therapeutic candidates.
Utilise molecular biology techniques for the evaluation of cell populations, therapeutic candidates and biomarkers.
Prepare cell supernatants, cell and tissue extracts for protein analysis.
Work with primary human cells and tissues ex vivo to evaluate efficacy of therapeutic candidates.
Assist senior personnel in the laboratory to carry out experiments.
Prepare experimental protocols and scientific reports.
Present scientific data at Group, Project Team and Departmental level.
Perform data analysis using routine spreadsheet and graphing platforms and flow cytometry software (Excel, Prism (or statistical analysis programs e.g. JMP, R-Studio/R- related skills) and FlowJo)
Organise and maintain the laboratory and laboratory records.
About You
To be successful, you will bring:
Tertiary degree with honours in relevant discipline (e.g. Biological Sciences, Immunology or Molecular Biology).
2+ years research experience in relevant scientific discipline in industry or academia.
Experience with mammalian cell culture and handling human blood products.
Experience in flow cytometry (eg. Cytek Aurora, MACSQuant).
Experience in establishing and performing cell-based functional assays.
Experience in writing scientific reports using an electronic notebook.
Knowledge of statistical analysis of data.
Knowledge of GLP.
Scientific curiosity and passion for solving scientific problems in a research environment.
Ability to work either independently with limited supervision or as part of a team environment.
APPLY NOW if you are looking love working in a lab, optimising and troubleshooting assays and solving problems which ultimately contribute to improving patient health.
About CSL Behring
CSL Behring is a global biotherapeutics leader driven by our promise to save lives. Focused on serving patients’ needs by using the latest technologies, we discover, develop and deliver innovative therapies for people living with conditions in the immunology, hematology, cardiovascular and metabolic, respiratory, and transplant therapeutic areas. We use three strategic scientific platforms of plasma fractionation, recombinant protein technology, and cell and gene therapy to support continued innovation and continually refine ways in which products can address unmet medical needs and help patients lead full lives.
CSL Behring operates one of the world’s largest plasma collection networks, CSL Plasma. Our parent company, CSL, headquartered in Melbourne, Australia, employs 32,000 people, and delivers its lifesaving therapies to people in more than 100 countries.
To learn more about CSL, CSL Behring, CSL Seqirus and CSL Vifor visit https://www.csl.com/ and CSL Plasma at https://www.cslplasma.com/.
Our Benefits
For more information on CSL benefits visit How CSL Supports Your Well-being | CSL.
You Belong at CSL
At CSL, Inclusion and Belonging is at the core of our mission and who we are. It fuels our innovation day in and day out. By celebrating our differences and creating a culture of curiosity and empathy, we are able to better understand and connect with our patients and donors, foster strong relationships with our stakeholders, and sustain a diverse workforce that will move our company and industry into the future.
To learn more about inclusion and belonging visit https://www.csl.com/careers/inclusion-and-belonging
Equal Opportunity Employer
CSL is an Equal Opportunity Employer. If you are an individual with a disability and need a reasonable accommodation for any part of the application process, please visit https://www.csl.com/accessibility-statement.
