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South San Francisco, California, United States
Hybrid
Within the AstraZeneca Cell Therapy Enterprise, our ambition is to realize the full potential of cell therapy for people living with cancer, immune-mediated and rare diseases around the world. This unit has responsibility for the value chain from discovery through to late-stage development and commercialization. We are rapidly progressing a broad pipeline of cell therapies in collaboration with AstraZeneca’s Therapeutic Area Units.
The Strategy and Commercial Executive Director, Cell Therapy Strategy and Commercial (CTSC), is a high-impact leadership role accountable for shaping and driving the end-to-end strategy for a defined indication or disease area within Cell Therapy. You will lead global commercial and strategic initiatives within the Cell Therapy Enterprise CTU)—including business development and competitive intelligence—partnering with Therapeutic Areas on clinical strategy, collaborating with in-market commercial and medical affairs on launch readiness, and aligning with global pricing and brand teams. Working cross-functionally with senior leaders, you will define early asset, disease, and portfolio strategies through PH3IDs. Reporting to the VP, Cell Therapy Strategy and Commercial, you will be a key architect of the company’s Cell Therapy strategy and lead cross-functional execution.
Key Accountabilities:
Deliver end-to-end Strategy, including:
Clear understanding and prioritization of current and future unmet needs
Indication-level strategic vision for both near-term and long-term
Integrated clinical strategy across all cell therapy platforms within the same indication
Work with global Clinical and ClinOps within respective TAs to develop comprehensive development strategy
Competitive early pipeline / long-term portfolio and life cycle management
Above-asset initiatives (e.g., Translational Medicine, Precision Medicine, Data Sciences)
Own insights generation for R&D and commercial activities
Lead global commercial cell therapy within indication
Build the referral capabilities between specific disease areas and the Cell Therapy delivery centers
Partners closely across different areas of Cell Therapy, Global Commercial, in-market commercial and medical affairs teams to ensure execution of global strategy
Lead and collaborate with cross-functional teams (e.g., GPTs, Clinical Development, Discovery, BD, Lifecycle and Pipeline, Competitive Intelligence) to develop disease area strategy content
Provide strategic counselling to Global Clinical Strategy Head (GCSH), Global Commercial and Medical Affairs leadership, and other senior leaders
Basic Qualifications:
BA/BS and 10 years of experience in life sciences or consulting firm with focus in life science programs
OR MS/MBA and 8+ years of experience in life sciences or consulting firm with focus in life science programs
OR PhD or MD and 5+ of experience in life sciences or consulting firm with focus in life science programs
Ability to interact and communicate effectively with senior executive teams.
Demonstrated ability to lead and influence experienced professionals.
Ability to think critically, creatively and to anticipate and solve problems.
Ability to navigate and be successful in a fast-paced, highly-matrixed work environment
Preferred Qualifications:
Strong analytical and communication skills
Strong business acumen and strategic thinking skills preferably demonstrated in a pharma related environment.
Effective interpersonal and relationship management skills with consultative approach and ability to interact and build trust
Operational effectiveness, highly organized process with follow through
Strong initiative to understand our core business goals and establish processes or programs to set direction, generate alignment and push forward
Financial background and understanding of forecasts, budgets, financial activities and tools
Resourceful, motivated, influential and proactive; able to prioritize in a fast-growing organization
Experience in strategic planning processes and tools
Scientific background
Understanding of the pharmaceutical business (including R&D)
Experience in translating business needs into a coordinated plan from cross-functional senior leadership team
Ability to develop creative and simple solutions to complex problems
In-Office Working Requirements
When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That’s why we work, on average, a minimum of three days per week from the office. But that doesn’t mean we’re not flexible. This role can be based in Gaithersburg MD, Boston MA, South San Francisco CA, New York NY.
The annual base pay for this position ranges from $267,914 to $401,870. Our positions offer eligibility for various incentives—an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.
Date Posted
24-Sep-2026Closing Date
Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.
