Manager, PRC Coordinator, Promotional Review & Operations Boston, MA (US)
We are seeking a Manager, PRC Coordinator, Promotional Review & Operations (PRO) to lead the end-to-end performance of the promotional review portfolio across assigned therapeutic areas and business priorities.
This role integrates portfolio planning, submission readiness, workflow orchestration, launch execution, stakeholder alignment, lifecycle management, performance monitoring, and continuous improvement, all while maintaining compliance with applicable policies, SOPs, and the US PRC Operations Manual.
This is not a meeting-administration role. You will exercise sound judgment, lead cross-functional operating rhythms, challenge avoidable defects and delays, and translate portfolio signals into clear actions, owners, dates, escalations, and measurable improvement.
Responsibilities
Strategic Portfolio Leadership
- Integrated operating view: Own the operating view for assigned portfolios, including launch, campaign, reapproval, expiration, and business-as-usual demand, maintaining an integrated plan of priorities, dependencies, owners, and dates.
- Risk anticipation: Use demand, aging, quality, capacity, and workflow signals to identify emerging risks, recommend sequencing, and escalate decisions when launch and business-as-usual priorities compete.
- Planning & Prioritization forums: Prepare and facilitate forums that convert forecasts and business priorities into executable review plans and clearly documented commitments.
- Cross-functional partnership: Partner with Commercial, Medical, Regulatory, Legal, Compliance, Business Operations, agencies, vendors, and PRO leaders to align expectations and sustain decision continuity.
End-to-End PRC Operations & Governance
- Full-cycle coordination: Coordinate intake, readiness, routing, review cycles, PRC and ad hoc meetings, decision and action documentation, final-upload verification, approved-release handoffs, reapproval, expiration alerts, and withdrawal follow-up.
- Workflow compliance: Ensure materials are routed through the correct workflow, are review-ready, and meet applicable requirements, policies, SOPs, and operating standards.
- Audit-ready records: Maintain accurate agendas, annotations, status communications, decisions, actions, and records, following up through documented closure.
- Escalation pathways: Initiate and support approved escalation pathways, including ERC escalation when applicable, and document final decisions and required follow-through.
Submission Excellence Program Leadership
- Readiness checklists: Apply approved intake and readiness checklists to identify missing references, metadata, annotations, support, or other package defects before review.
- Defect documentation: Consistently document rejection, rework, and defect reasons; distinguish coordinator checks from specialist or reviewer judgment and route questions to the appropriate owner.
- Trend analysis: Use monthly and in-cycle signals to identify repeat defects and material trends, without deferring urgent risk action while awaiting formal reports.
- Documented interventions: Lead interventions with Project Owners and agencies using specific examples, agreed corrective actions, accountable owners, due dates, and effectiveness checks.
- Sustained improvement: Monitor improvement in subsequent cycles, escalate overdue or recurring issues, and contribute to Submission Excellence training, job aids, and operating standards.
Launch Readiness & Priority Execution
- Launch planning: Partner with launch leads and business stakeholders to establish review forecasts, priority order, reviewer commitments, meeting cadence, dependencies, and contingency coverage for launch-critical materials.
- Capacity management: Anticipate volume surges and timing conflicts, surface capacity constraints early, and recommend practical mitigation plans.
- Operational balance: Maintain disciplined launch execution while protecting business-as-usual continuity and keeping risks, decisions, and recovery actions visible.
Performance, Aging & Continuous Improvement
- Metrics monitoring: Monitor volume, cycle time, aging, review readiness, quality, rework, and recurring defects, and translate findings into targeted actions.
- Aging interventions: Intervene on aging materials at defined checkpoints, documenting the blocker, next action, owner, and resolution date, and escalating material risk before timelines are exceeded.
- Process improvement: Identify and lead process, system, meeting, and operating-model improvements in partnership with PRO Process, Systems, Lifecycle, and Analytics colleagues.
- Quality & CAPA support: Support root-cause analysis, CAPA/deviation evidence collection, corrective-action tracking, and effectiveness checks when required.
Stakeholder, Agency & Vendor Management
- Trusted operating partner: Serve as the primary coordination point for assigned portfolios, communicating priorities, accountabilities, risks, and decisions clearly and promptly.
- Standards accountability: Hold Project Owners, agencies, and vendors to approved readiness, workflow, quality, and follow-through expectations while maintaining constructive relationships.
- Onboarding & training: Support onboarding and training of stakeholders on PRC processes, policies, SOPs, systems, and role responsibilities.
- Coverage & continuity: Coordinate with service providers and backup resources to maintain coverage and continuity, and flag scope, capacity, or service-standard concerns to PRO leadership.
Systems, Data Integrity & Knowledge Management
- Data accuracy: Maintain accurate records, metadata, ownership, distribution lists, rosters, calendars, templates, and portfolio documentation in approved systems and repositories.
- System enablement: Support system enhancements, user acceptance testing, adoption, and change communications relevant to coordinator workflows.
- Audit traceability: Protect audit traceability and ensure operating documents, decisions, and handoffs are accessible, current, and sustainable during transitions.
Leadership & Team Contribution
- Proactive ownership: Model critical thinking, responsiveness, and escalation discipline; operate independently with sound judgment and minimal oversight.
- Team collaboration: Provide backup coverage, share portfolio knowledge, and support standardized coordinator practices across the broader PRO organization.
- Coaching: Coach newer coordinators and contribute practical scenarios, playbooks, and lessons learned to coordinator qualification and continuous learning.
Decision Rights & Accountability
- Makes day-to-day coordination, sequencing, and escalation recommendations within approved PRC governance and portfolio priorities.
- Owns operational follow-through and evidence; specialist medical, legal, regulatory, compliance, commercial, and contractual decisions remain with the authorized functional owners.
- Escalates unresolved risk, conflicting priorities, recurring quality issues, and material capacity gaps with supporting facts and a recommended path forward.
Mandatory Requirements
- Bachelor's degree or equivalent relevant experience.
- Experience in promotional review, MLR/PRC operations, regulated content operations, marketing operations, or a comparable cross-functional environment.
- Demonstrated ability to manage complex portfolios, facilitate senior cross-functional stakeholders, and deliver through ambiguity.
- Working knowledge of promotional material workflows, submission readiness, lifecycle controls, records discipline, and regulated operating procedures.
- Strong analytical judgment, with the ability to interpret operational metrics, identify root causes, and convert insights into action.
- Excellent facilitation, written communication, stakeholder management, prioritization, and problem-solving skills.
Desirable Qualifications
- Experience with Veeva Vault PromoMats or a comparable review and approval system.
- Demonstrated launch or high-volume/campaign readiness experience (strongly preferred).
- Experience in pharmaceutical, biotech, medical, or other regulated promotional review environments.
- Experience supporting launch materials, expedited reviews, lifecycle management, SOPs, training, or process improvement initiatives.
- Experience working with agencies of record, vendors, and cross-functional review teams.
The annual base pay for this position ranges from $115,000- $173,000 USD Annual. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. Our positions offer eligibility for various incentives—an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.
Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.
AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.
Date Posted
09-nov-2026
Closing Date
29-nov-2026
Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.
