Scientist, Probe Design

Advanced Cell Diagnostics, Inc. (ACD) is a leader in the field of molecular pathology and tissue-based diagnostics. Our core RNAscope® technology is the world’s first multiplex fluorescent and chromogenic in situ hybridization platform capable of detecting and quantifying RNA biomarkers in situ at single molecule sensitivity. RNAscope® is an ideal platform for developing the next generation of tissue-based companion diagnostics. We are committed to continued innovation to bridge the gap between basic research and clinical medicine to fulfill the promise of personalized medicine.
The Scientist, Probe Design is a key member of the R&D team. The Scientist will work within a highly dynamic group to develop and optimize new probe products based on our RNAscope® technology and work closely with our commercial team to identify and support customer needs.
Responsibilities

• Design made-to-order RNAscope probes for target sequences using proprietary software

• Answer technical inquiries related to design of target probes & submission of New Probe Requests (NPR)

• Review NPR forms for accurate and efficient probe designs

• Utilize Linux command-line tools for sequence alignments (BLAST/BLAT), probe selection, specificity

• Provide probe product training and troubleshooting for Advanced Cell Diagnostics scientific probe product lines via phone and email

• Act as primary contact for customers regarding technical issues, as well as providing scientific consultation for research use only inquiries

• Collaborate with Commercial and Marketing teams to meet the needs of customers

• Ensure customer service excellence and guaranteed response times by actively monitoring SalesForce queue, inbox, phone calls, and ensuring all issues are resolved in a timely and comprehensive manner

• Contribute to ongoing new product development and introduction with R&D teams in a laboratory environment

• Contribute to the ongoing development of the Probe Design team's knowledgebase

• Present scientific and product updates to customers and internal teams

Qualifications
Education:

• PhD with 4+ years of research experience in molecular biology, bioinformatics computational biology or a closely related field

Skills:

• In-depth knowledge of genes and sequences, RNA biology

• Familiarity with standard bioinformatics tools (Python, R, or equivalent), and a programming language (C/C++, Java)

• Experience in commonly used biological databases and bioinformatics software tools

• Ability to work within multi-disciplinary team of computational biologists, molecular biologists, imaging software scientists, biochemists and others

• Post-graduate experience with experimental design, cell and molecular techniques

• Must be very adept at diagnosing, troubleshooting and solving complex technical problems with a variety of biological assays

• Highly self-directed, conscientious, articulate, and possesses excellent presentation and teaching skills

Experience:

• 2yr+ of experience in Biotech/Biopharma R&D

• 2yr+ of experience with Linux, Python, Perl or other programming languages

• 2yr+ of experience with next-generation sequencing platforms or sequencing tools (genomic/epigenomic/transcriptomic)

• Prior experience in probe design across multiple species

• Experience in biological sequence analysis tasks such as database searches and multiple sequence alignment tools

• Committed to total customer satisfaction with outstanding interpersonal skills and professionalism

• Customer-facing experience with a strong scientific capacity

Working Conditions:

• Ability to travel ~10% of time

• Work is performed in office settings.

• Regular use of computers.

• Work may occasionally require extended hours to meet project deadlines.

Physical Requirements:

• Prolonged periods of sitting or standing at a computer.