Scientist, RC Discovery Biology

Fusion Pharmaceuticals, part of the AstraZeneca Group, is redefining precision oncology with next‑generation radioconjugates that deliver powerful alpha‑emitting payloads directly to tumors. Our pipeline spans multiple first‑in‑class programs—backed by a GMP‑compliant, brand new radiopharmaceutical facility in Hamilton, we’re turning groundbreaking science into real‑world impact for patients. Join us at the forefront of radiopharma innovation and be part of turning breakthrough science into meaningful outcomes for patients—come build what’s next with us!

The Role:

We are seeking a highly motivated, hands-on Scientist, RC Discovery Biology to support portfolio programs through model development, mechanism of action studies, assay development, and in vitro characterization of radioconjugates. This role is ideal for a strong laboratory scientist who thrives in a fast-paced research environment and enjoys working across disciplines to generate high-quality data that advances discovery and development programs. The successful candidate will contribute to the design, execution, analysis, and reporting of a broad range of cellular, molecular, and biochemical assays. Working closely with cross-functional colleagues in biology, chemistry, and radiochemistry, this individual will help build robust in vitro capabilities to support target evaluation, candidate profiling, and translational decision-making across the portfolio.

Responsibilities:

• Establish, maintain, and optimize mammalian cell culture systems to support candidate profiling and biological evaluation.
• Design and perform experiments assays to characterize radioconjugates and investigate biological activity.
• Apply methods such as immunohistochemistry (IHC), flow cytometry, ELISA, western blotting, and related assays to generate high-quality experimental data.
• Support the development, optimization, validation, and troubleshooting of new in vitro assays to address evolving project and platform needs.
• Analyze, interpret, and clearly communicate experimental findings through reports, presentations, and team discussions.
• Maintain accurate, detailed, and well-organized laboratory records with strong attention to data quality and integrity.
• Work effectively with biologists, chemists, radiochemists, and other scientific colleagues to support project milestones and team objectives.
• Ensure compliance with Good Laboratory Practice, Safety, Health and Environment standards and all other relevant internal AstraZeneca standards and external regulations

Qualifications:

• MSc. with at least 2 years or B.Sc. with at least 5 years of post-graduate academic or industry experience in Molecular/Cell Biology, Immunology, and/or Biochemistry
• Hands-on academic or industry experience in a laboratory-based biology role supporting in vitro research.
• Demonstrated experience with biochemical and cell biology methods such as cell culture, immunohistochemistry, flow cytometry, ELISA, and western blotting.
• Experience developing, optimizing, and executing cell-based and biochemical assays.
• Demonstrated safe handling of chemical and biohazardous materials
• Ability to adapt to, perform, and develop unfamiliar methods in a rapidly evolving research
• Ability to generate high-quality, reproducible, and well-documented data with strong attention to detail.
• Ability to troubleshoot experiments and adapt methods in a rapidly evolving research environment.
• Strong written and verbal communication skills, with the ability to clearly present data and scientific conclusions.
• Ability to work effectively in a multi-disciplinary team and contribute to shared scientific goals.
• Strong time management skills and the ability to manage multiple priorities effectively.
• Experience working with radioisotopes is considered an asset

Great People want to Work with us! Find out why:

• GTAA Top Employer Award for 11 years
• Top 100 Employers Award
• Canada’s Most Admired Corporate Culture
• Learn more about working with us in Canada
• View our YouTube channel

Are you interested in working at AZ, apply today!

AstraZeneca is an equal opportunity employer that is committed to diversity and inclusion and providing a workplace that is free from discrimination. AstraZeneca is committed to accommodating persons with disabilities. Such accommodation is available on request in respect of all aspects of the recruitment, assessment and selection process and may be requested by emailing AZCHumanResources@astrazeneca.com.

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Annual base salary for this position ranges from 82,377.60 to 108,120.60.

AstraZeneca is committed to providing fair and equitable compensation opportunities to all colleagues. Our compensation policies and practices have been designed to allow colleagues to progress through the salary range over time as they progress in their role. The range provided in this posting represents an offer pay range used in a majority of situations. The base pay offered will vary depending on multiple individualized factors, including the candidate's skills and experience, job-related knowledge, and other specific business and organizational needs.  In some cases, offers outside the range may also be considered to address unique circumstances.

In addition, our permanent positions offer an annual Variable Pay Bonus/Short Term Incentive opportunity as well as eligibility to participate in our equity-based long-term incentive program (if applicable to role).  Benefits offered for permanent roles include a competitive Flex Benefits & Retirement Savings Program, 4 weeks’ paid vacation, and annual Personal Days. Fixed Term Contract/Temporary positions (excluding students) are offered a Contract Benefits Program.

We are using AI as part of the recruitment process.

This advertisement relates to a current vacancy.