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Boston, Massachusetts, United States
Remote only
Centessa Pharmaceuticals, a wholly owned subsidiary of Eli Lilly and Company, is a clinical-stage company developing orexin receptor 2 (OX2R) agonists as a new class of medicines for the treatment of narcolepsy and potentially other sleep-wake disorders. Centessa’s lead investigational candidate – cleminorexton (formerly ORX750) – is being developed for narcolepsy type 1, narcolepsy type 2, and idiopathic hypersomnia. Centessa's OX2R agonist portfolio includes additional clinical and preclinical-stage assets with potential utility across a broader range of neurological, neurodegenerative, and neuropsychiatric conditions.
Headquartered in Boston, Massachusetts, Centessa was recognized as a Great Place to Work® in 2026.
Description of Role
We are seeking an experienced, collaborative, and scientifically rigorous Senior Advisor, Molecular Pharmacology to provide scientific leadership, at the Associate Director level, for molecular pharmacology activities supporting neuroscience discovery and development programs.The successful candidate will bring a strong foundation in pharmacology and apply broad scientific expertise to address questions related to compound pharmacology, receptor and target biology, signaling mechanisms, and translation across relevant experimental systems.
The ideal candidate will combine deep scientific expertise with curiosity, strategic thinking, and the ability to identify and implement experimental approaches that address evolving program needs. The individual will work collaboratively across multidisciplinary teams and with internal and external scientific partners to develop pharmacology strategies, guide experimental work, interpret complex data, and advance therapeutic programs.
Key Responsibilities
Qualifications
Compensation
The annual base salary range for this position is $130,000.00 to $180,000.00. Individual compensation within this range will be determined based on a variety of factors, including location, qualifications, skills, relevant experience, and job knowledge.
In addition to base pay, this role is eligible for a discretionary annual bonus. The Company also offers a comprehensive benefits package, which includes a 401(k) plan, company-sponsored medical, dental, vision, and life insurance, generous paid time off, and a health and wellness program.
Work Location
The Senior Advisor, Molecular Pharmacology role is a remote role based in the US, with occasional travel.
POSITION: Full-Time, Exempt
EEOC Statement: Centessa Pharmaceuticals, a wholly owned subdisary of Eli Lilly and Company believes in a diverse environment and is committed to equal employment opportunity for all its employees and qualified applicants. We do not discriminate in recruitment, hiring, training, promotion, or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. We will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
Please note: We will not assign referral rights for any unsolicited resumes from recruitment agencies.
